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KMID : 0363320180390020259
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Journal of Korean Oriental Internal Medicine
2018 Volume.39 No. 2 p.259 ~ p.267
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A Case Report of Chemotherapy-Induced Hand-Foot Syndrome Treated with Modified Dohongsamul-tang
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Han Ga-Jin
Jang Myung-Woong
Seong Shin
Kim Sung-Su
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Abstract
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Hand-foot syndrome (HFS) frequently occurs after receiving chemotherapy, such as sorafenib, in patients with hepatocellular carcinoma (HCC), and this impairs quality of life (QOL). The prevalence of HFS due to sorafenib is 10-28%. The effective methods to treat HFS are not established aside from temporary discontinuation of chemotherapy agents and drug dosage adjustment because the mechanism of HFS has not been elucidated. According to a previous study, modified Dohongsamul-tang was effective in the treatment of patients with HFS and improved patients’ QOL. Based on these results, we administered the soaking method with modified Dohongsamul-tang to a 50-year-old male patient with HCC complaining of HFS due to sorafenib. After two weeks, the symptoms of HFS were improved despite taking sorafenib. We suggest that modified Dohongsamul-tang is a novel method for treating HFS.
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KEYWORD
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hand-foot syndrome, Dohongsamul-tang, sorafenib, medicine, Korean traditional, case reports
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